When you are stuck on a problem, sometimes it is best to stop thinking about it—consciously, anyway. Research has shown that taking a break or a nap can help the brain create1to a solution. Now a new study2on the effect of this so-called incubation（潜伏期）by using sound cues to focus the sleeping mind on a targeted problem.
When humans sleep, parts of the brain replay certain memories, strengthening and transforming them. About a decade ago researchers developed a technique, called targeted memory reactivation（TMR）, aimed at further enhancing3memories: when a sound becomes associated with a memory and is later played during sleep, that memory gets4. In a study published last November in Psychological Science, scientists tested whether5the memory of a puzzle during sleep might also improve problem-solving.
About 60 participants visited the laboratory before and after a night of6. First, they7spatial, verbal and conceptual puzzles, with a distinct music clip repeating in the background for each, until they had worked on six puzzles they could not solve. Overnight they wore electrodes（电极）to detect slow-wave sleep, which may be important for memory enhancement—and a device played the sounds 8to three of the six unsolved puzzles. The next day, back at the lab, the participants attempted the six puzzles again. (Each repeated the experiment with a different set of puzzles the following night.) All told, the subjects solved 32 percent of the sound-stimulated puzzles compared with 21 percent of the 9puzzles.
The researchers "very bravely went for quite complex tasks that involved a lot of complex processing, and remarkably they found these really strong effects in all of their 10." says Penny Lewis, a psychologist at Cardiff University, who was not involved in the research. "These are supercool results. Now we need to go out and try to understand them by firstly replicating（复制）them and secondly trying to 11the component processes that are actually being influenced."
Beyond providing new evidence that humans restructure memories while sleeping the research may have 12implications. "In a futuristic world, maybe TMR could help us use sleep to work on our problems," says lead author Kristin Sanders, who was a graduate student at Northwestern University during the study. Sleep-monitoring technology is increasingly accessible—and even without devices, prospective solvers can focus on important problems before 13.
Still, sleep is not 14; people need to do their homework and load their heads with the puzzle pieces involved. "I'm not going to solve cancer with this technique," Sanders says, "because I am totally 15cancer research."
